Khi một giáo sư phát triển một loại vắc-xin giúp loại bỏ chứng dị ứng của con người với chó, ông vô tình phá vỡ sự cân bằng quyền lực mong manh giữa mèo và chó, đồng thời châm ngòi cho một cuộc chiến khốc liệt giành quyền thống trị thế giới thú cưng. Cuộc chiến trở nên căng thẳng khi phe mèo, do ông Tinkles dẫn đầu, đối đầu với chú chó con ngây thơ Lou và những người bạn chó của cậu.

Full

Jeff Goldblum

Elizabeth Perkins

Alexander Pollock

Miriam Margolyes

Tobey Maguire

Alec Baldwin

Sean Hayes

Susan Sarandon

Joe Pantoliano

Michael Clarke Duncan

Jon Lovitz

Charlton Heston

Glenn Ficarra

Billy West

John Michael Higgins

When a professor develops a vaccine that eliminates human allergies to dogs, he unwittingly upsets the fragile balance of power between cats and dogs and touches off an epic battle for pet supremacy. The fur flies as the feline faction, led by Mr. Tinkles, squares off against wide-eyed puppy Lou and his canine cohorts.

United States

Lawrence Guterman

Cats & Dogs

Village Roadshow Pictures

NPV Entertainment

Mad Chance

Zide-Perry Productions

BenderSpink

Warner Bros. Pictures

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